Bus Greyhound Us0421 - New York - Pittsburgh - St. Louis: Full Schedule in Columbus

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List of stops
              Map

              St Louis Bus Station – New York Port Authority

              St Louis Bus Station

              08:4513:55

              Terre Haute Greyhound Station

              13:00
              13:05
              18:05
              18:10

              Indianapolis Bus Station

              14:30
              15:35
              19:20
              19:55

              Dayton Trotwood Bus Station

              18:00
              18:30
              21:50
              22:00

              Springfield (Love's)

              19:10
              19:40
              22:40
              23:00

              Columbus Bus Station

              20:30
              20:50
              23:50
              00:20 +1

              Columbus (E Mound St)

              21:05
              21:10
              00:35 +1
              00:40 +1

              Pittsburgh Intermodal Station

              00:20 +1
              01:35 +1
              03:50 +1
              06:05 +1

              Harrisburg Bus Station

              05:30 +1
              05:40 +1
              10:15 +1
              10:25 +1

              Norristown (Park & Ride)

              07:20 +112:05 +1
              12:10 +1

              Philadelphia

              08:10 +1
              08:20 +1
              13:00 +1
              13:10 +1

              Camden Walter Rand Trans Center

              13:20 +1
              13:25 +1

              Westampton Academy Park & Ride

              14:05 +1
              14:10 +1

              Newark (Nj)

              09:50 +1
              10:00 +1
              15:30 +1
              15:40 +1

              New York Port Authority

              10:30 +116:20 +1
              Times marked with "—" indicate that the vehicle does not stop at this stop.
              The schedule is provided in the local timezone. Times with "(+1)" indicate departures on the next day.

              New York Port Authority – St Louis Bus Station

              Times marked with "—" indicate that the vehicle does not stop at this stop.
              The schedule is provided in the local timezone. Times with "(+1)" indicate departures on the next day.
              Times marked with "—" indicate that the vehicle does not stop at this stop.
              The schedule is provided in the local timezone. Times with "(+1)" indicate departures on the next day.
              Last updated on April 1, 2026
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              Route Path (Streets & Roads)

              Outbound: St Louis Bus Station – New York Port Authority
              South 15th Street - Cherry Street - West South Street - Salem Avenue - Ridge Road - North Wilson Road - East Mound Street - Liberty Avenue - Market Street - King of Prussia Road - Spring Garden Street - Broadway - Western Drive - Raymond Plaza West - West 41st Street
              Inbound: New York Port Authority – St Louis Bus Station
              West 41st Street - Spring Garden Street - King of Prussia Road - Market Street - Liberty Avenue - Main Street - Southgate Parkway - East Mound Street - North Wilson Road - Ridge Road - West South Street - South 15th Street
              All data is available in GTFS feed: flix-bus-us

              Bus Greyhound Us0421 FAQ

              • What time does the Greyhound Us0421 bus start operating?

                Services on the Greyhound Us0421 - New York - Pittsburgh - St. Louis bus start at 08:45 on Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, Sunday.

              • What time does the Greyhound Us0421 bus stop working?

                Services on the Greyhound Us0421 - New York - Pittsburgh - St. Louis bus stop at 16:20 +1 on Monday, Tuesday, Wednesday, Thursday, Friday, Saturday, Sunday.

              • Is there a Greyhound Us0421 bus stop near me?

                Click here to view the nearest Greyhound Us0421 - New York - Pittsburgh - St. Louis bus stop.

              Greyhound Us0421 (Columbus Buses)

              The first stop of the Greyhound Us0421 bus route is St Louis Bus Station and the last stop is New York Port Authority. Greyhound Us0421 (New York - Pittsburgh - St. Louis) is operational during everyday.

              Additional information: Greyhound Us0421 has 15 stops and the total trip duration for this route is approximately 1585 minutes.

              See why over 2 million users trust and consider busmaps.com as the best public transport website. busmaps gives you Columbus Buses suggested routes, real-time bus tracker, line route maps in Columbus, and helps to find the closest Greyhound Us0421 bus stops near you. No internet available? Download an offline PDF map and bus schedule for the Greyhound Us0421 bus to take on your trip.

              Greyhound Us0421 bus near me