221 Bus - Druten - Nijmegen CS - Heijendaal

List of stops
      Monday to Friday

      Druten, Tijdelijk Busstation – Nijmegen, Huygensgebouw

      Druten, Tijdelijk Busstation

      06:3006:4507:0007:1007:2007:3007:4007:4507:5008:0008:1008:2008:3008:4008:5009:0009:1009:2009:3109:4610:0110:1610:3110:4611:0111:1611:3111:4612:0112:1612:3112:4513:0013:1513:3013:45—14:00—14:15—14:30—14:45—15:00—15:1515:28——15:43—15:58—16:1216:2216:3216:4216:5217:0517:1517:2217:3017:4017:5018:0018:1518:3018:4519:0019:1519:3019:4520:00

      Druten, Scharenburg/N322

      06:3306:4807:0307:1307:2307:3307:4307:4807:5308:0308:1308:2308:3308:4308:5309:0309:1309:2309:3409:4910:0410:1910:3410:4911:0411:1911:3411:4912:0412:1912:3412:4813:0313:1813:3313:48—14:03—14:18—14:33—14:48—15:03—15:1815:31——15:46—16:01—16:1516:2516:3516:4516:5517:0817:1817:2517:3317:4317:5318:0318:1818:3318:4819:0319:1819:3319:4820:03

      Nijmegen, Poort Neerbosch

      06:4507:0007:1507:2507:3707:4707:5708:0208:0708:1708:2708:3708:4708:5709:0709:1509:2509:3509:4610:0110:1610:3110:4611:0111:1611:3111:4612:0112:1612:3112:4613:0013:1513:3013:4514:00—14:15—14:30—14:45—15:00—15:15—15:3015:43——15:58—16:13—16:2716:3716:4716:5717:0717:2017:3017:3717:4517:5518:0518:1518:3018:4519:0019:1519:3019:4520:0020:15

      Nijmegen, Dr. de Blecourtstraat

      06:4707:0207:1807:2807:4007:5008:0008:0508:1008:2008:3008:4008:5009:0009:0909:1709:2709:3709:4810:0310:1810:3310:4811:0311:1811:3311:4812:0312:1812:3312:4813:0313:1813:3313:4814:03—14:18—14:33—14:48—15:03—15:18—15:3315:46——16:01—16:16—16:3016:4016:5017:0017:1017:2317:3317:4017:4817:5818:0818:1718:3218:4719:0219:1719:3219:4720:0220:17

      Nijmegen, Energiew./Wolfskuilsew.

      06:4907:0407:2007:3007:4207:5208:0208:0708:1208:2208:3208:4208:5209:0209:1109:1909:2909:3909:5010:0510:2010:3510:5011:0511:2011:3511:5012:0512:2012:3512:5013:0513:2013:3513:5014:05—14:20—14:35—14:50—15:05—15:20—15:3515:48——16:03—16:18—16:3216:4216:5217:0217:1217:2517:3517:4217:5018:0018:1018:1918:3418:4919:0419:1919:3419:4920:0420:19

      Nijmegen, Scheepvaartweg

      06:5007:0507:2207:3207:4407:5408:0408:0908:1408:2408:3408:4408:5409:0409:1309:2109:3109:4109:5210:0710:2210:3710:5211:0711:2211:3711:5212:0712:2212:3712:5213:0713:2213:3713:5214:07—14:22—14:37—14:52—15:07—15:22—15:3715:50——16:05—16:20—16:3416:4416:5417:0417:1417:2717:3717:4417:5218:0218:1218:2018:3518:5019:0519:2019:3519:5020:0520:20

      Nijmegen, Industrieweg

      06:5107:0607:2307:3307:4507:5508:0508:1008:1508:2508:3508:4508:5509:0509:1409:2209:3209:4209:5310:0810:2310:3810:5311:0811:2311:3811:5312:0812:2312:3812:5313:0813:2313:3813:5314:08—14:23—14:38—14:53—15:08—15:23—15:3815:51——16:06—16:21—16:3516:4516:5517:0517:1517:2817:3817:4517:5318:0318:1318:2118:3618:5119:0619:2119:3619:5120:0620:21

      Nijmegen, Vlietstraat

      06:5207:0707:2607:3607:4807:5808:0808:1308:1808:2808:3808:4808:5809:0709:1609:2409:3409:4409:5510:1010:2510:4010:5511:1011:2511:4011:5512:1012:2512:4012:5513:1013:2513:4013:5514:10—14:25—14:40—14:55—15:10—15:25—15:4015:53——16:08—16:23—16:3716:4716:5717:0717:1717:3017:4017:4717:5518:0518:1518:2218:3718:5219:0719:2219:3719:5220:0720:22

      Nijmegen, Zwaluwstraat

      06:5307:0807:2807:3807:5008:0008:1008:1508:2008:3008:4008:5009:0009:0809:1709:2509:3509:4509:5610:1110:2610:4110:5611:1111:2611:4111:5612:1112:2612:4112:5613:1213:2713:4213:5714:12—14:27—14:42—14:57—15:12—15:27—15:4215:55——16:10—16:25—16:3916:4916:5917:0917:1917:3217:4217:4917:5718:0718:1718:2318:3818:5319:0819:2319:3819:5320:0820:23

      Nijmegen, Centraal Station

      06:5607:1107:33
      07:36
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      14:2914:3114:4314:4614:5815:0115:0915:16
      15:19
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      15:49
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      16:2616:2916:3616:43
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      17:5318:0118:1118:2118:2618:4118:5619:1119:2619:4119:5620:1120:26

      Nijmegen, Station Heyendaal

      ——07:3907:4908:0108:1108:2108:2608:3108:4108:5109:0109:1109:1709:2609:3409:4409:5410:0510:2010:3510:5011:0511:2011:3511:5012:0512:2012:3512:5013:0513:2213:3713:5214:0714:2214:32—14:46—15:01—15:1215:2215:32—15:4215:52—16:0216:1216:2016:29—16:3916:4916:5917:0917:1917:2917:4217:52—————————————

      Nijmegen, Huygensgebouw

      ——07:4107:5108:0308:1308:2308:2808:3308:4308:5309:0309:1309:1909:2809:3609:4609:5610:0710:2210:3710:5211:0711:2211:3711:5212:0712:2212:3712:5213:0713:2413:3913:5414:0914:2414:34—14:48—15:03—15:1415:2415:34—15:4415:54—16:0416:1416:2216:31—16:4116:5117:0117:1117:2117:3117:4417:54—————————————
      Times marked with "—" indicate that the vehicle does not stop at this stop.

      Nijmegen, Huygensgebouw – Druten, Tijdelijk Busstation

      Nijmegen, Huygensgebouw————————07:4107:5108:0308:1308:2308:2808:33—08:4308:53—09:03—09:1309:19—09:2809:3609:46—09:5610:0710:2210:3710:5211:0711:2211:3711:5212:0712:2212:3712:5213:0713:2413:3913:5414:0914:2414:3414:4815:0315:1415:2415:3415:4415:5416:0416:1416:2216:3116:4116:5117:0117:1117:2117:3117:4417:54———————
      Nijmegen, Erasmusgebouw————————07:4207:5208:0408:1408:2408:2908:34—08:4408:54—09:04—09:1409:20—09:2909:3709:47—09:5710:0810:2310:3810:5311:0811:2311:3811:5312:0812:2312:3812:5313:0813:2513:4013:5514:1014:2514:3514:4915:0415:1515:2515:3515:4515:5516:0516:1516:2316:3316:4316:5317:0317:1317:2317:3317:4617:55———————
      Nijmegen, Spinozagebouw————————07:4407:5408:0608:1608:2608:3108:36—08:4608:56—09:06—09:1609:22—09:3109:3909:49—09:5910:1010:2510:4010:5511:1011:2511:4011:5512:1012:2512:4012:5513:1013:2713:4213:5714:1214:2714:3714:5115:0615:1715:2715:3715:4715:5716:0716:1716:2516:3516:4516:5517:0517:1517:2517:3517:4817:57———————
      Nijmegen, Radboudumc————————07:4607:5608:0808:1808:2808:3308:38—08:4808:58—09:08—09:1809:24—09:3309:4109:51—10:0110:1210:2710:4210:5711:1211:2711:4211:5712:1212:2712:4212:5713:1213:2913:4413:5914:1414:2914:3914:5315:0815:1915:2915:3915:4915:5916:0916:1916:2716:3716:4716:5717:0717:1717:2717:3717:4917:58———————
      Nijmegen, Han————————07:4707:5708:0908:1908:2908:3408:39—08:4908:59—09:09—09:1909:25—09:3409:4209:52—10:0210:1310:2810:4310:5811:1311:2811:4311:5812:1312:2812:4312:5813:1313:3013:4514:0014:1514:3014:4014:5415:0915:2015:3015:4015:5016:0016:1016:2016:2816:3816:4816:5817:0817:1817:2817:3817:5017:59———————
      Nijmegen, Station Heyendaal————————07:4907:5908:1108:2108:3108:3608:41—08:5109:01—09:11—09:2109:27—09:3609:4409:54—10:0410:1510:3010:4511:0011:1511:3011:4512:0012:1512:3012:4513:0013:1513:3213:4714:0214:1714:3214:4214:5615:1115:2315:3315:4315:5316:0316:1316:2316:3116:4116:5117:0117:1117:2117:3117:4117:5218:01———————
      Nijmegen, Centraal Station06:2906:4507:0007:1007:2007:3007:4007:5007:55
      07:58
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      09:53
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      10:24
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      18:07
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      18:1918:2818:4318:5819:1319:2819:58
      Nijmegen, Zwaluwstraat06:3206:4807:0307:1307:2307:3307:4307:5308:0108:1108:2308:3308:43——08:57——09:12—09:27——09:42—09:56—10:11—10:2710:4210:5711:1311:2811:4311:5812:1312:2812:4312:5813:1313:2813:4514:0014:1514:3014:4514:5515:0915:2415:3515:4515:5516:0516:1516:2516:3516:4516:5517:0517:1517:2517:3517:4517:5518:0418:1318:2218:3118:4619:0119:1619:3120:01
      Nijmegen, Vlietstraat06:3406:5007:0507:1507:2507:3507:4507:5508:0308:1308:2508:3508:45——08:59——09:14—09:29——09:44—09:58—10:13—10:2910:4410:5911:1511:3011:4512:0012:1512:3012:4513:0013:1513:3013:4714:0214:1714:3214:4714:5715:1115:2615:3715:4715:5716:0716:1716:2716:3716:4716:5717:0717:1717:2717:3717:4717:5718:0618:1518:2418:3318:4819:0319:1819:3320:03
      Nijmegen, Industrieweg06:3506:5107:0607:1607:2607:3607:4607:5608:0408:1408:2608:3608:46——09:00——09:15—09:30——09:45—09:59—10:14—10:3010:4511:0011:1611:3111:4612:0112:1612:3112:4613:0113:1613:3113:4814:0314:1814:3314:4814:5815:1215:2715:3815:4815:5816:0816:1816:2816:3816:4816:5817:0817:1817:2817:3817:4817:5818:0718:1618:2518:3418:4919:0419:1919:3420:04
      Nijmegen, Scheepvaartweg06:3606:5207:0807:1807:2807:3807:4807:5808:0608:1608:2808:3808:48——09:02——09:17—09:32——09:47—10:01—10:16—10:3210:4711:0211:1811:3311:4812:0312:1812:3312:4813:0313:1813:3313:5014:0514:2014:3514:5015:0015:1415:2915:4015:5016:0016:1016:2016:3016:4016:5017:0017:1017:2017:3017:4017:4917:5918:0818:1718:2618:3518:5019:0519:2019:3520:05
      Nijmegen, Energiew./Wolfskuilsew.06:3806:5407:1007:2007:3007:4007:5008:0008:0808:1808:3008:4008:50——09:04——09:19—09:34——09:49—10:03—10:18—10:3410:4911:0411:2011:3511:5012:0512:2012:3512:5013:0513:2013:3513:5214:0714:2214:3714:5215:0215:1615:3115:4215:5216:0216:1216:2216:3216:4216:5217:0217:1217:2217:3217:4217:5118:0118:1018:1918:2818:3718:5219:0719:2219:3720:07
      Nijmegen, Dr. de Blecourtstraat06:4006:5607:1207:2207:3207:4207:5208:0208:1008:2008:3208:4208:52——09:06——09:21—09:36——09:51—10:05—10:20—10:3610:5111:0611:2211:3711:5212:0712:2212:3712:5213:0713:2213:3713:5414:0914:2414:3914:5415:0415:1815:3315:4415:5416:0416:1416:2416:3416:4416:5417:0417:1417:2417:3417:4417:5318:0318:1218:2118:3018:3918:5419:0919:2419:3920:09
      Nijmegen, Poort Neerbosch06:4206:5807:1407:2407:3407:4407:5408:0408:1208:2208:3408:4408:54——09:08——09:23—09:38——09:53—10:07—10:22—10:3810:5311:0811:2411:3911:5412:0912:2412:3912:5413:0913:2413:3913:5614:1114:2614:4114:5615:0615:2015:3515:4615:5616:0616:1616:2616:3616:4616:5617:0617:1617:2617:3617:4617:5518:0518:1418:2318:3218:4118:5619:1119:2619:4120:11
      Druten, Scharenburg/N32206:5407:1007:2707:3707:4707:5708:0708:1708:2508:3508:4708:5709:07——09:21——09:35—09:50——10:05—10:19—10:34—10:5011:0511:2011:3611:5112:0612:2112:3612:5113:0613:2113:3613:5114:0814:2314:3814:5315:0815:1815:3315:4815:5916:0916:1916:2916:3916:4916:5917:0917:1917:2917:3917:4917:5818:0718:1718:2618:3518:4418:5319:0819:2319:3819:5320:23
      Druten, Tijdelijk Busstation06:5807:1807:3807:4807:5808:0808:1808:2808:3608:4608:5809:0809:18——09:25——09:39—09:54——10:09—10:23—10:38—10:5411:0911:2411:4011:5512:1012:2512:4012:5513:1013:2513:4013:5514:1214:2714:4214:5715:1215:2615:4115:5616:0716:1716:2716:3716:4716:5717:0717:1717:2717:3717:4717:5318:0218:1118:2118:3018:3918:4818:5719:1219:2719:4219:5720:27
      Times marked with "—" indicate that the vehicle does not stop at this stop.
      Times marked with "—" indicate that the vehicle does not stop at this stop.
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      Route Path (Streets & Roads)

      Outbound: Druten, Tijdelijk Busstation – Nijmegen, Huygensgebouw
      Van Heemstraweg - Scharenburg - Neerbosscheweg - Energieweg - Industrieweg - Marialaan - Tunnelweg - Heyendaalseweg
      Inbound: Nijmegen, Huygensgebouw – Druten, Tijdelijk Busstation
      Heyendaalseweg - Erasmuslaan - Philips van Leydenlaan - Kapittelweg - Tunnelweg - Marialaan - Industrieweg - Energieweg - Neerbosscheweg - Scharenburg - Van Heemstraweg

      Schedules and stops for this route are published in GTFS: nationaal-toegangspunt-its

      Frequently asked questions about route 221

      • What time does route 221 start operating?

        Services on route 221 start at 06:30 from Monday to Friday.

      • What time does route 221 stop operating?

        Services on route 221 end at 20:26 from Monday to Friday.

      • Is there a stop for route 221 near me?

        View the nearest stop for route 221.

      221 (Arnhem Buses)

      The first stop of the 221 bus route is Druten, Tijdelijk Busstation and the last stop is Nijmegen, Huygensgebouw. 221 (Druten - Nijmegen CS - Heijendaal) is operational during on weekdays.

      Additional information: 221 has 12 stops. The total trip duration for this route is approximately 43 minutes.

      More than 5 million users trust busmaps.com for public transport information. Find suggested Buses routes in Arnhem, real-time vehicle tracking, route maps, nearby stops, and offline PDF schedules.

      221 bus near me

      Last updated on November 11, 2026